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Aestimo Innovator’s Briefings (AIB) were Multi stakeholder focused reports:

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  • Medics

  • Healthcare Administrators

  • Patient Associations

  • Policy Makers

  • Funders

  • Industry

  • Regulators

  • Reimbursement bodies

  • Patients

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These reports integrate

 

  • Overview of key characteristics of the disease

 

  • The patient journey from symptoms, through diagnosis and treatment to follow up

 

  • Ongoing global development statistics in the specific indication

 

  • Ongoing global clinical trial design metrics (median patient number, median duration and median cost)

  • Continental region-specific indication prevalence and incidence rates (the latter, region specific or global) for either:​

                     -European Union

                     -North America

                     -Latin America and the Caribbean

                     -Africa and the Middle East

                     -Asia

 

  • The Standards of Care (existing products and solutions):​

                     -Class

                     -Application within the eligible patient population

                     -Examples

                     -Treatment cost based upon treatment regimen and region-specific

                      intervention price

 

  • The annual maximum market value of the classes of intervention within the specific geography (Serviceable Available Market – SAM value)

 

  • Forecasting (lifetime Serviceable Obtainable Market – SOM value) for the generation of a new product in each class, that would be better than the standard of care and sold at the same price to enable reimbursement

 

  • Lifetime revenue requirements necessary to achieve a Return on Investment via de novo development or repositioning of an existing validated intervention

 

  • De Novo and Repositioning Risk assessment for the development of the new product, generic or biosimilar in the region-specific marketplace

 

  • HTA/Health economics and patient reported outcomes overview of the components that determine if a new solution is reimbursable compared to the standard of care  

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  • References and recommended reading

 

They create a global innovation map focused on patient-need, designed to inform and enable all healthcare innovation stakeholders to determine validity, competitive value and investment requirement for a better healthcare, everywhere.

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The complete list of Innovation Briefings for all major diseases includes Cancer, Neurological, Cardiovascular, Metabolic, Musculoskeletal, Female Reproductive Health, Infectious diseases and Mental Health, and can be found at http://www.echino.eu/aib

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