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Aestimo Innovator’s Briefings (AIB) were Multi stakeholder focused reports:

  • Medics

  • Healthcare Administrators

  • Patient Associations

  • Policy Makers

  • Funders

  • Industry

  • Regulators

  • Reimbursement bodies

  • Patients

These reports integrate

 

  • Overview of key characteristics of the disease

 

  • The patient journey from symptoms, through diagnosis and treatment to follow up

 

  • Ongoing global development statistics in the specific indication

 

  • Ongoing global clinical trial design metrics (median patient number, median duration and median cost)

  • Continental region-specific indication prevalence and incidence rates (the latter, region specific or global) for either:​

                     -European Union

                     -North America

                     -Latin America and the Caribbean

                     -Africa and the Middle East

                     -Asia

 

  • The Standards of Care (existing products and solutions):​

                     -Class

                     -Application within the eligible patient population

                     -Examples

                     -Treatment cost based upon treatment regimen and region-specific

                      intervention price

 

  • The annual maximum market value of the classes of intervention within the specific geography (Serviceable Available Market – SAM value)

 

  • Forecasting (lifetime Serviceable Obtainable Market – SOM value) for the generation of a new product in each class, that would be better than the standard of care and sold at the same price to enable reimbursement

 

  • Lifetime revenue requirements necessary to achieve a Return on Investment via de novo development or repositioning of an existing validated intervention

 

  • De Novo and Repositioning Risk assessment for the development of the new product, generic or biosimilar in the region-specific marketplace

 

  • HTA/Health economics and patient reported outcomes overview of the components that determine if a new solution is reimbursable compared to the standard of care  

  • References and recommended reading

 

They create a global innovation map focused on patient-need, designed to inform and enable all healthcare innovation stakeholders to determine validity, competitive value and investment requirement for a better healthcare, everywhere.

The complete list of Innovation Briefings for all major diseases includes Cancer, Neurological, Cardiovascular, Metabolic, Musculoskeletal, Female Reproductive Health, Infectious diseases and Mental Health, and can be found at http://www.echino.eu/aib

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